Dr. Shashi Bala Singh
Director, NIPER Hyderabad
Dr. Shashi Bala Singh a Distinguished Scientist and Director General, Life Sciences (DG LS) in Defence Research and Development Organisation till 31 May 2018. Prior to DGLS she was Scientist ‘H’/Outstanding Scientist and Director of Defence Institute of Physiology and Allied Sciences (DIPAS), Delhi since 2010. A person with strong will, she has the distinction of serving as the Director of Defence Institute of High Altitude Research (DIHAR), Leh, from 2007 to 2010.
She is an alumni of All India Institute of Medical Sciences (AIIMS) where she obtained her Ph.D. degree in Human Physiology in 1986 and started her career in DRDO at DIPAS, Delhi in 1990. She was awarded D.Sc. from Bharathiar University in 2014.
Dr. Shashi Bala Singh has worked extensively in the area of High Altitude physiology and has made remarkable contributions in improving the quality of life of the soldiers deployed at high altitudes. She has identified novel mechanisms of hypophagia and cognitive impairment and several signaling pathways and molecular mechanisms underlying morbidities associated with high altitude hypoxia. She worked on various behavioral, biochemical and electrophysiological studies which proved that impairment in memory function is mainly due to the oxidative stress leading to neuro-degeneration in brain structures (hippocampus, cortex and striatum) involved in learning and memory. She also worked on development of supplements with antioxidant and cholinomimetic drugs to improve high altitude induced impairment in cognitive functions. She has been instrumental in guiding studies on understanding adaptation, maladaptation, performance enhancement and rapid acclimatization using intermittent hypoxia.